Toxicity Profile of Aqueous Leaf Extracts of Citropsis Articulata and Mystroxylon Aethiopicum in Male Albino Rats
Abstract Aim: Many serious adverse effects of new xenobiotics are detected thorough toxicological studies. In this present study, the safety profile of C.articulata L. (Rutaceae) and M.aethiopicum (Celastraceae) leaf aqueous extracts was evaluated by acute and sub-chronic toxicity tests in male wistar rats. Methods: Acute oral toxicity was investigated in 8 weeks old Swiss mice (18-24g) that were divided in 4 groups (n=4mice) given extract doses ranging from 7,500-12,000 mg/kg and 15,000-22,500...